Basic Information
VIS ID
TVIS30016477
Fusion event
HIV-TULP4 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
q25.3
Reference genome
GRCh37/hg19
Start
158655712/158234680 (Hg38)
End
158655758/158234680 (Hg38)
Orient
+
Location type
Intronic
Target gene
TULP4
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-186-5p ; hsa-mir-32-5p ; hsa-mir-484 ; hsa-mir-28-5p ; hsa-mir-25-3p ; hsa-mir-92a-3p ; hsa-mir-363-3p ; hsa-mir-367-3p ; hsa-mir-92b-3p ; hsa-mir-3688-3p ; hsa-mir-4694-3p ; hsa-mir-4261 ; hsa-mir-578 ; hsa-mir-5047 ; hsa-mir-1301-3p ; hsa-mir-7156-3p ; hsa-mir-6881-3p ; hsa-mir-877-3p ; hsa-mir-487a-3p ; hsa-mir-154-3p ; hsa-mir-107 ; hsa-mir-103a-3p ; hsa-mir-134-5p ; hsa-mir-197-3p ; hsa-mir-3118 ; hsa-mir-6080 ; hsa-mir-6773-3p ; hsa-mir-6879-3p ; hsa-mir-943
Nearest miRNA
hsa-mir-10398/Upstream/705480; hsa-mir-1913/Downstream/375027;
Nearest TSS
ENST00000381078/Upstream/2444; ENST00000432358/Downstream/47583;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/1642, chr6-CpG: 28/Downstream/281573
Nearby gene
GTF2H5(No orient, 35336)
Upstream sequence
GTGGCTCAGCTATGCATGTGATTTGTAAAATGCATTTAAAAACTGAGTACAACCTCTTATGAAATGCTGTGATTTAGTTACTGCATGGGTTTCTGTTTAG
Downstream sequence
tacatttgtctttagtgagacttcatggaatatgtaattaaaatgtcaaatgtgttttaatttggctgagataatgttaatttagtTACTAAATTGTAAC
Target sequence
CATTCTGTGCAGCAtttcagtattaccaaaagccttacagaaattg
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate