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TVIS30016484
Basic Information
VIS ID
TVIS30016484
Fusion event
HIV-RNF216 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
p22.1
Reference genome
GRCh37/hg19
Start
5804715/5765084 (Hg38)
End
5804938/5765084 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA7B
Target gene
RNF216
miRNAs that regulate target gene
hsa-mir-455-3p
;
hsa-mir-320a
;
hsa-mir-376a-3p
;
hsa-mir-20a-5p
;
hsa-mir-106b-5p
;
hsa-mir-5089-5p
;
hsa-mir-4279
;
hsa-mir-1200
;
hsa-mir-4465
;
hsa-mir-26b-5p
;
hsa-mir-26a-5p
;
hsa-mir-1297
;
hsa-mir-1911-5p
;
hsa-mir-6506-5p
;
hsa-mir-619-5p
;
hsa-mir-1976
;
hsa-mir-3653-5p
;
hsa-mir-6747-3p
;
hsa-mir-6727-3p
;
hsa-mir-4722-3p
;
hsa-mir-544b
;
hsa-mir-4324
;
hsa-mir-660-3p
;
hsa-mir-6513-3p
;
hsa-mir-8062
;
hsa-mir-7851-3p
;
hsa-mir-619-3p
;
hsa-mir-5698
;
hsa-mir-744-3p
;
hsa-mir-1178-3p
;
hsa-mir-891a-3p
;
hsa-mir-143-5p
;
hsa-mir-4430
;
hsa-mir-3652
;
hsa-mir-122-5p
;
hsa-mir-504-3p
;
hsa-mir-3140-3p
;
hsa-mir-3135b
;
hsa-mir-3934-3p
;
hsa-mir-6499-3p
;
hsa-mir-5693
;
hsa-mir-484
;
hsa-mir-3155b
;
hsa-mir-3155a
;
hsa-mir-19b-3p
;
hsa-mir-19a-3p
;
hsa-mir-519d-3p
;
hsa-mir-20b-5p
;
hsa-mir-93-5p
;
hsa-mir-17-5p
;
hsa-mir-4662a-3p
Nearest miRNA
hsa-mir-339/Upstream/53174; hsa-mir-10399/Downstream/1301880;
Nearest TSS
ENST00000635602/Upstream/3946;
ENST00000416608/Downstream/15208;
Nearest CpG islands
None/Target,
chr7-CpG: 39/Upstream/156731
,
chr7-CpG: 91/Downstream/15929
Upstream sequence
gcttgagcccatgagttccaagtttacagtaagctatgaccaacccactgcactccagcctaggaaacaaagcaagactctcttaaaaaaaaaaaaaaaa
Downstream sequence
aaattagctgggtgtggtagcaggtgggaatctgtaatcccagctacttgggaggctgaggtaagagaattgcttcagcttggaaggtggaggttgcagt
Target sequence
gtaaggatgggataaaacaatttttacacattcaaagactaagagagtttacctcccacagatactcaaagagctattaaaaaaatgaacttcaAgaccgggcatggtggctcacgcctttaatcccaggacttcgggaggtcgaggccagtggattgcttaaggtcaggagttgagaccagcctgggcaacacagtgaggactatctatactgaaaatacaa
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT5
Sample type
PBMC
Age
44
Gender
Male
CpG Island Information
×
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