Basic Information
VIS ID
TVIS30016487
Fusion event
HIV-RPA3 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
p21.3
Reference genome
GRCh37/hg19
Start
7703008/7663377 (Hg38)
End
7702900/7663377 (Hg38)
Orient
-
Location type
Intronic
Target gene
RPA3
miRNAs that regulate target gene
hsa-mir-26b-5p ; hsa-mir-615-3p
Nearest miRNA
hsa-mir-339/Upstream/596332; hsa-mir-10399/Downstream/10463843;
Nearest TSS
ENST00000635602/Upstream/22405; ENST00000406829/Downstream/55230;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/22329, chr7-CpG: 81/Downstream/305849
Upstream sequence
TTTTTTCTTTCTTTGTTTTTCTTTCATTTTTTAAAAGTCTGAGCATAAATAAGAGAGGTGGAAGTAAAATTTATGTTAATCAATTTAATTAATTAGTTTC
Downstream sequence
CAAGCTGTTCTGTGGAGCTGAAAAGTGACATCAGTTTAAATGTCTTCTCTTGCTTATCCTCTCAGGCATCTGTACCTCTTCCCCATTACACCAATATCAA
Target sequence
TAAGATAGTTTTTTCTTTCTTTGTTTTTCTTTCATTTTTTAAAAGTCTGAGCATAAATAAGAGAGGTGGAAGTAAAATTTATGTTAATCAATTTAATTAATTAGTTTC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate