Basic Information
VIS ID
TVIS30016489
Fusion event
HIV-chr7 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
p21.3
Reference genome
GRCh37/hg19
Start
7795480/7755849 (Hg38)
End
7795744/7755849 (Hg38)
Orient
+
Location type
Intronic
Nearest miRNA
hsa-mir-339/Upstream/688804; hsa-mir-10399/Downstream/10371371;
Nearest TSS
ENST00000635602/Upstream/37242; ENST00000406829/Downstream/16512;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/114801, chr7-CpG: 81/Downstream/213377
Upstream sequence
ACTACCAAAAACATGCTGGCTAAGTACGTATGTAATGTTAGCATCCCAGTGCCACTAGTGCAAGGCAGACTCCCATGAGCCATTTAAACATAAAAGTTAA
Downstream sequence
CTAAAACTAGGCATAGTGTGAAGTTGGACCCCAAAGGGTAAAGACGGTTGTTGGAAAATGAAGATAGCCTTTTCTGTGGAAGATCAGGCAAGTAACCACC
Target sequence
GAAGGTAGAATTTTAGAAGTTTTAATGATTATTTGAAATCTCAAGGGATTCTTATACAAGATATGGTGATGGTTATAAATATATGGACTGACACACACTTATCACTAAATAAATGTTTTACATGAACAAATGAGTAAACAAGTAAACCACATTGCTTGGAATAAGTAGTGTTTGTTAGAGCTTTGAGCCCTGGGAGCGGGGGACTCAAGAAATAGGGAGACTTAATCAGAAAGAAAGGACTATGAAGTGATATCA
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate