Basic Information
VIS ID
TVIS30016494
Fusion event
HIV-SNX13 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
p21.1
Reference genome
GRCh37/hg19
Start
17898509/17858886 (Hg38)
End
17898540/17858886 (Hg38)
Orient
+
Location type
Intronic
Target gene
SNX13
miRNAs that regulate target gene
hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-136-5p ; hsa-mir-1226-3p ; hsa-mir-3591-3p ; hsa-mir-21-3p ; hsa-mir-124-3p ; hsa-mir-506-3p
Nearest miRNA
hsa-mir-339/Upstream/10791841; hsa-mir-10399/Downstream/268334;
Nearest TSS
ENST00000635602/Upstream/37189; ENST00000455069/Downstream/41220;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/559409, chr7-CpG: 82/Downstream/81265
Upstream sequence
gaagaggccagaatcagaaccaaacatattagagcaaactgatattttagtaaggtgccaaggaaattaattttatgaaaaagtcttttcaacaaatggt
Downstream sequence
atcaatctaaactgtcatattccacacacataaaaatgtgagataaatcatagaacaaaatataaaagtaaaaattataaaacttagcataggcaaataa
Target sequence
gctagaatatctagatgtctgtattttaaaa
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate