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TVIS30016497
Basic Information
VIS ID
TVIS30016497
Fusion event
HIV-OSBPL3 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
p15.3
Reference genome
GRCh37/hg19
Start
24858415/24818796 (Hg38)
End
24858150/24818796 (Hg38)
Orient
-
Location type
Intronic
Target gene
OSBPL3
miRNAs that regulate target gene
hsa-mir-103a-3p
;
hsa-mir-21-5p
;
hsa-mir-16-5p
;
hsa-mir-4762-3p
;
hsa-mir-3192-3p
;
hsa-mir-4662a-5p
;
hsa-mir-3151-3p
;
hsa-mir-6890-3p
;
hsa-mir-3163
;
hsa-mir-449b-3p
;
hsa-mir-6807-3p
;
hsa-mir-217
;
hsa-mir-6499-3p
;
hsa-mir-539-5p
;
hsa-mir-6838-5p
;
hsa-mir-4519
;
hsa-mir-497-5p
;
hsa-mir-424-5p
;
hsa-mir-195-5p
;
hsa-mir-15b-5p
;
hsa-mir-15a-5p
;
hsa-mir-1252-3p
;
hsa-mir-3646
;
hsa-mir-548e-5p
;
hsa-mir-4712-3p
;
hsa-mir-4757-3p
;
hsa-mir-4517
;
hsa-mir-181d-5p
;
hsa-mir-181b-5p
;
hsa-mir-181c-5p
;
hsa-mir-181a-5p
Nearest miRNA
hsa-mir-1183/Upstream/3347650; hsa-mir-10399/Downstream/1131123;
Nearest TSS
ENST00000635602/Upstream/3703;
ENST00000607375/Downstream/30540;
Nearest CpG islands
None/Target,
chr7-CpG: 39/Upstream/60928
,
chr7-CpG: 134/Downstream/160584
Upstream sequence
catgagggcagatttaagcccagctacatctacaatcacaacaaacggaaatggtttacacaacctacataaaaggcagagaaatgtcaggctgggttac
Downstream sequence
aaagcaagattTGGGAATCCTAGGCCCATGGAAATAGGTAGATTGCTCAGGAAAAGGCTGATGGGGAAGTATGGCCTAGGAGAAGGATGCTAAGGCTGAG
Target sequence
acataaatcctaaagtaacaactttaacaagaaacaaaacaggtaagtatagctaataagctaacaggggagatgaaagagaatgatagaaattattcaatccaaaaggcagagaaagaggaaacggagaacaaagaacagatgtgacaaacagaaaagaaacatcatgagggcagatttaagcccagctacatctacaatcacaacaaacggaaatggtttacacaacctacataaaaggcagagaaatgtcag
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT1
Sample type
PBMC
Age
47
Gender
Male
CpG Island Information
×
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