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TVIS30016501
Basic Information
VIS ID
TVIS30016501
Fusion event
HIV-ZNRF2 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
p14.3
Reference genome
GRCh37/hg19
Start
30359729/30320113 (Hg38)
End
30359698/30320113 (Hg38)
Orient
-
Location type
Intronic
Target gene
ZNRF2
miRNAs that regulate target gene
hsa-mir-103a-3p
;
hsa-mir-4328
;
hsa-mir-6868-5p
;
hsa-mir-3128
;
hsa-mir-4720-5p
;
hsa-mir-4799-3p
;
hsa-mir-5588-5p
;
hsa-mir-503-5p
;
hsa-mir-548c-3p
;
hsa-mir-4524a-5p
;
hsa-mir-4524b-5p
;
hsa-mir-15a-5p
;
hsa-mir-16-5p
;
hsa-mir-15b-5p
;
hsa-mir-195-5p
;
hsa-mir-424-5p
;
hsa-mir-486-5p
;
hsa-mir-497-5p
;
hsa-mir-4274
;
hsa-mir-4519
;
hsa-mir-6772-3p
;
hsa-mir-6838-5p
;
hsa-mir-5189-3p
;
hsa-mir-8054
;
hsa-mir-548l
;
hsa-mir-548k
;
hsa-mir-548av-5p
;
hsa-mir-559
;
hsa-mir-548y
;
hsa-mir-548w
;
hsa-mir-548o-5p
;
hsa-mir-548j-5p
;
hsa-mir-548i
;
hsa-mir-548h-5p
;
hsa-mir-548d-5p
;
hsa-mir-548c-5p
;
hsa-mir-548bb-5p
;
hsa-mir-548b-5p
;
hsa-mir-548ay-5p
;
hsa-mir-548au-5p
;
hsa-mir-548as-5p
;
hsa-mir-548ar-5p
;
hsa-mir-548aq-5p
;
hsa-mir-548ap-5p
;
hsa-mir-548am-5p
;
hsa-mir-548ak
;
hsa-mir-548ae-5p
;
hsa-mir-548ad-5p
;
hsa-mir-548ab
;
hsa-mir-548a-5p
;
hsa-mir-3191-5p
;
hsa-mir-4470
;
hsa-mir-6824-3p
;
hsa-mir-6764-3p
;
hsa-mir-330-5p
;
hsa-mir-326
;
hsa-mir-518c-5p
;
hsa-mir-3675-3p
;
hsa-mir-3973
;
hsa-mir-548al
;
hsa-mir-129-5p
;
hsa-mir-3680-3p
;
hsa-mir-557
;
hsa-mir-507
;
hsa-mir-450b-5p
;
hsa-mir-106a-3p
;
hsa-mir-6722-5p
;
hsa-mir-548x-5p
;
hsa-mir-548g-5p
;
hsa-mir-548f-5p
;
hsa-mir-548aj-5p
;
hsa-mir-1229-5p
;
hsa-mir-4314
;
hsa-mir-3132
;
hsa-mir-197-5p
;
hsa-mir-4448
;
hsa-mir-4268
;
hsa-mir-6776-5p
;
hsa-mir-6861-5p
;
hsa-mir-646
;
hsa-mir-548n
;
hsa-mir-100-5p
Nearest miRNA
hsa-mir-1183/Upstream/30223; hsa-mir-10399/Downstream/2412868;
Nearest TSS
ENST00000635602/Upstream/34539;
ENST00000628121/Downstream/42287;
Nearest CpG islands
None/Target,
chr7-CpG: 39/Upstream/34088
,
chr7-CpG: 68/Downstream/158258
Upstream sequence
catgtgtgtactacctgtgtgtccgtgagtttatatatttatttaaccacgaattctttgttttgattcatctgttggttgAGTCCTGAGTCTGAGTATT
Downstream sequence
TAAAGATAATACACTTCTTGAGTCCCATTTTTTTCCAAGAGCTCTGAAGACCCCTCTGCCATGTGTCCCAAATAATtatctatatatgttatatatgtag
Target sequence
atctgttggttgAGTCCTGAGTCTGAGTATT
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT1
Sample type
PBMC
Age
47
Gender
Male
CpG Island Information
×
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