Basic Information
VIS ID
TVIS30016508
Fusion event
HIV-VPS41 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
p14.1
Reference genome
GRCh37/hg19
Start
38812538/38772938 (Hg38)
End
38812627/38772938 (Hg38)
Orient
+
Location type
Intronic
Target gene
VPS41
miRNAs that regulate target gene
hsa-mir-148a-3p ; hsa-let-7b-5p ; hsa-mir-197-3p ; hsa-mir-4634 ; hsa-mir-4695-3p ; hsa-mir-6787-3p ; hsa-mir-6511b-3p ; hsa-mir-6511a-3p ; hsa-mir-6736-3p ; hsa-mir-4714-3p ; hsa-mir-652-3p ; hsa-mir-30e-5p ; hsa-mir-30d-5p ; hsa-mir-30b-5p ; hsa-mir-30c-5p ; hsa-mir-30a-5p
Nearest miRNA
hsa-mir-1183/Upstream/1853506; hsa-mir-10399/Downstream/4377957;
Nearest TSS
ENST00000635602/Upstream/7185; ENST00000464276/Downstream/2734;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/141377, chr7-CpG: 36/Downstream/203005
Upstream sequence
ATATTTAAGTGTAAAAATACTTGACCAAAAAGCAAGAGAGGGAAGGAGAAGGACAGAAAGGGAGGGAATGACATACTAAAAAACTTGAAAAAAAAATAAG
Downstream sequence
ATTCATCTACTGTATATAAATTTTATTTGTGGCCATTTACAGCATTGTTCTACTTTTACAGAACAATTACACCCCATGGTCAGCGATAAATGTTTCCTCC
Target sequence
GTGAGTTTAAAATTCTACGTTTAATACATCAACACTCTGACTTCAGCTGAAAAAGTGTTAAAAATTCTCTATGTCTACTGCATATTAGA
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate