Basic Information
VIS ID
TVIS30016514
Fusion event
HIV-CCM2 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
p13
Reference genome
GRCh37/hg19
Start
45101685/45062086 (Hg38)
End
45101717/45062086 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA7D
Target gene
CCM2
Nearest miRNA
hsa-mir-1183/Upstream/180286; hsa-mir-10399/Downstream/11893699;
Nearest TSS
ENST00000635602/Upstream/23825; ENST00000480382/Downstream/2517;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/61428, chr7-CpG: 66/Downstream/26294
Upstream sequence
tcctctctgctggtgctggctctagggtttctgccccgcaatgagctgtgattcttagcattgcatatctgtctctccatctttggggttattgtttttt
Downstream sequence
acagtcattgattttaagtttgccagctttcttgttgtgaggatgggagtgatgacttctgagcctttacaagctggacaggaaattggaaAGTCCCATT
Target sequence
catgtgacctcaattatctgatggatctgaga
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate