Basic Information
VIS ID
TVIS30016515
Fusion event
HIV-chr7 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
p12.2
Reference genome
GRCh37/hg19
Start
50336516/50296920 (Hg38)
End
50336335/50296920 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1183/Upstream/5415120; hsa-mir-10399/Downstream/6658865;
Nearest TSS
ENST00000635602/Upstream/21298; ENST00000484847/Downstream/7148;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/137530, chr7-CpG: 212/Downstream/6379
Nearby gene
IKZF1(No orient, 7861)
Nearest cancer related gene
IKZF1(TSG, No orient, 7861)
Upstream sequence
AGGTCGTTCCCTTTCATGGAGAACAGACAATGACAACTCAACCACAAtgataatggaccaaacacctgaagccagtaaggggggtgggcaggcagaaatc
Downstream sequence
caggggagaaccttctaggagacagcagtaagtgaaaggcagtgagctggtctggagcacttgaggactataaggtagggccaagtggccagagacaggc
Target sequence
CTTTCAATGAGAGCAAACAACAAATGTTACCAATGAAAACCAGAGAGAAGGCAGGAGAAAAGCTAACGCTCGGGTGGGTCAAGGTCGTTCCCTTTCATGGAGAACAGACAATGACAACTCAACCACAAtgataatggaccaaacacctgaagccagtaaggggggtgggcaggcagaaatc
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate