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TVIS30016520
Basic Information
VIS ID
TVIS30016520
Fusion event
HIV-PHTF2 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q21.11
Reference genome
GRCh37/hg19
Start
77537588/77908271 (Hg38)
End
77537305/77908271 (Hg38)
Orient
-
Location type
Intronic
Target gene
PHTF2
miRNAs that regulate target gene
hsa-mir-375
;
hsa-mir-215-5p
;
hsa-mir-192-5p
;
hsa-let-7a-5p
;
hsa-mir-17-5p
;
hsa-mir-20a-5p
;
hsa-mir-93-5p
;
hsa-mir-106a-5p
;
hsa-mir-106b-5p
;
hsa-mir-20b-5p
;
hsa-mir-519c-3p
;
hsa-mir-526b-3p
;
hsa-mir-519b-3p
;
hsa-mir-519d-3p
;
hsa-mir-519a-3p
;
hsa-mir-590-3p
;
hsa-mir-548t-5p
;
hsa-mir-5589-3p
;
hsa-mir-548az-5p
;
hsa-mir-8055
;
hsa-mir-30a-5p
;
hsa-mir-32-5p
;
hsa-mir-92a-3p
;
hsa-mir-30c-5p
;
hsa-mir-30d-5p
;
hsa-mir-30b-5p
;
hsa-mir-186-5p
;
hsa-mir-30e-5p
;
hsa-mir-92b-3p
;
hsa-mir-4329
;
hsa-mir-3653-5p
;
hsa-mir-3672
;
hsa-mir-676-5p
;
hsa-mir-4495
;
hsa-mir-6864-3p
;
hsa-mir-802
;
hsa-mir-5096
;
hsa-mir-513b-5p
;
hsa-mir-27b-5p
;
hsa-mir-627-3p
;
hsa-mir-556-5p
;
hsa-mir-873-3p
;
hsa-mir-3140-5p
Nearest miRNA
hsa-mir-10525/Upstream/1993002; hsa-mir-10399/Downstream/14295744;
Nearest TSS
ENST00000635602/Upstream/2010;
ENST00000468351/Downstream/664;
Nearest CpG islands
None/Target,
chr7-CpG: 39/Upstream/108738
,
chr7-CpG: 140/Downstream/110863
Upstream sequence
ctgAGGTGGGAGAAATAAGAATGTATGATTGATGGATAAAGGAGGGAGACGAAGGTAAAGAGAGTTTATGTCCAGAAAGTCTAAGGGATGCTGTGTAGGC
Downstream sequence
AAAACAAGATTTCCCTTCATGTAGTAATAGTTAGCATTGATGGATGTTTAGTGGTTTCTCTGGAAACTATGCCTAAGTAAATTTGTTATTAATTCTAAGG
Target sequence
ccctagcaatttcattttttcatagtctttagtgtttgtgatctaggagaaaggtcttgaagcacctatattagtccctgaaaaagactgattggccctgcttaggtcacttgcccatctttttataagcttttgtattcagacttactaagactgtgacaagcctaggttacatgtctatccctgAGGTGGGAGAAATAAGAATGTATGATTGATGGATAAAGGAGGGAGACGAAGGTAAAGAGAGTTTATGTC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT1
Sample type
PBMC
Age
47
Gender
Male
CpG Island Information
×
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