Basic Information
VIS ID
TVIS30016521
Fusion event
HIV-TMEM243 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q21.12
Reference genome
GRCh37/hg19
Start
86830193/87200877 (Hg38)
End
86830267/87200877 (Hg38)
Orient
+
Location type
Intronic
Target gene
TMEM243
miRNAs that regulate target gene
hsa-mir-484
Nearest miRNA
hsa-mir-10525/Upstream/11285608; hsa-mir-10399/Downstream/5003138;
Nearest TSS
ENST00000635602/Upstream/1264; ENST00000412227/Downstream/2166;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/47999, chr7-CpG: 114/Downstream/18718
Upstream sequence
aagacaagattcagtgccaggcctcctttccctatttatgcttctcACCCAAAGAACAACCTAGAGTGCTAGTGCTGGTCTAGACAAAGATGTCAAGTGG
Downstream sequence
TGACTTTGTTCCACATTTTTGGATTTCTCCATATAACtgattttaatcatcctgatgaaaatatatctaaactttaatgaatactttcctgcctaccttt
Target sequence
CAGATGACACCTCAAAAAGCCTATTAGCAAAGTACTACACTGTGCTTACCTTTCAAGAATGATTTCCTCATGGG
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate