Basic Information
VIS ID
TVIS30016531
Fusion event
HIV-ZNF384 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
99093521/99495898 (Hg38)
End
99093563/99495898 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA7F
Target gene
ZNF384
miRNAs that regulate target gene
hsa-mir-16-5p ; hsa-mir-1-3p ; hsa-mir-155-5p ; hsa-mir-93-5p ; hsa-mir-1304-3p ; hsa-mir-374a-5p ; hsa-mir-7850-5p ; hsa-mir-4309 ; hsa-mir-3198 ; hsa-mir-27b-3p ; hsa-mir-27a-3p ; hsa-mir-513a-5p ; hsa-mir-19b-2-5p ; hsa-mir-19b-1-5p ; hsa-mir-19a-5p ; hsa-mir-4653-3p ; hsa-mir-2052 ; hsa-mir-1303 ; hsa-mir-5096 ; hsa-mir-4435 ; hsa-mir-222-5p ; hsa-mir-197-3p ; hsa-mir-6832-5p ; hsa-mir-193b-5p ; hsa-mir-3190-5p ; hsa-mir-3129-5p ; hsa-mir-199b-3p ; hsa-mir-199a-3p ; hsa-mir-936 ; hsa-mir-483-5p ; hsa-mir-892b ; hsa-mir-193b-3p ; hsa-mir-193a-3p ; hsa-mir-4284 ; hsa-mir-4772-3p ; hsa-mir-4485-5p ; hsa-mir-6890-3p ; hsa-mir-129-5p ; hsa-mir-3180-5p ; hsa-mir-329-5p
Nearest miRNA
hsa-mir-10525/Upstream/86634; hsa-mir-10399/Downstream/597662;
Nearest TSS
ENST00000635602/Upstream/11868; ENST00000451158/Downstream/2900;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/22662, chr7-CpG: 68/Downstream/3756
Upstream sequence
tttagtagagatggggtttcaccatgttggtcaggctggtctcaaactcctgacctcaggtgatccacctgccttggcctcccaaagtgttgggattact
Downstream sequence
agacagagtctcactctgtcacccaggttggagtgcaatggcgtgatctcggctcactgcaacctccacctcccaggttcaagtgattctcctgcctcag
Target sequence
ggcatgagccactgcacccagccTAtttattttatctttttg
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate