Basic Information
VIS ID
TVIS30016536
Fusion event
HIV-STAG3 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
99809601/100211978 (Hg38)
End
99809452/100211978 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA7F
Target gene
STAG3
Nearest miRNA
hsa-mir-10525/Upstream/55309; hsa-mir-10399/Downstream/144673;
Nearest TSS
ENST00000635602/Upstream/319; ENST00000471803/Downstream/3201;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/34018, chr7-CpG: 114/Downstream/59402
Upstream sequence
GAGTAGACCACCCTGCCCTTCTCTCTCAAGAACTAGGGGCTGATGTGCCAAAGAGAAGCCAGGGTGTTTCCCCTCTCTCCGCTCGGTGATGCCTGGTCTG
Downstream sequence
GAAAAGCTGAATGAATCTAGAGTAAAGGAGGACAGGTTATATGTTGGTTTGGACTTTGCTTGGACTCTACTTTTATTAAAGAATAAGGAAAAGAAATTAC
Target sequence
TAGAAATCCAGGATGAGTCAAATGAAGAACGGCAGGATACAGACATGGTGAGTAGACCACCCTGCCCTTCTCTCTCAAGAACTAGGGGCTGATGTGCCAAAGAGAAGCCAGGGTGTTTCCCCTCTCTCCGCTCGGTGATGCCTGGTCTG
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate