Basic Information
VIS ID
TVIS30016545
Fusion event
HIV-chr7 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
105717174/106076728 (Hg38)
End
105717453/106076728 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA7F
Nearest miRNA
hsa-mir-10525/Upstream/3605197; hsa-mir-10399/Downstream/8576617;
Nearest TSS
ENST00000635602/Upstream/48300; ENST00000609281/Downstream/16524;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/66941, chr7-CpG: 100/Downstream/34929
Nearby gene
SYPL1(No orient, 13777)
Upstream sequence
accctgtatatagtcttctctagcctgttcttttcactcaacagtgtttctgagacattcatgtggttggtaaagctgtagttccttaattttcacctct
Downstream sequence
ccttcaaactcaatattgtcacacaaaatttttatcaataggtgtaaaatggtatctctgtggttttgacttccatttccctgataatgaggttcaacag
Target sequence
gtgttatagtcccttgtgcgactctactaaaatttatattttttcctgccagtagatatccgagttgtttctatttctttctgtaagacaaacttttttgcttagaacaatcttctgtttcatattaggtgctaatgtttctcttgggtatataactagatgaggagttactgggtcttcaggcatgaacaaccttataaggtaatgacaaattattttccaaagtggttatattaatttacatttctaccagga
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
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