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TVIS30016548
Basic Information
VIS ID
TVIS30016548
Fusion event
HIV-MDFIC integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q31.1
Reference genome
GRCh37/hg19
Start
114616620/114976565 (Hg38)
End
114616416/114976565 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA7G
Target gene
MDFIC
miRNAs that regulate target gene
hsa-mir-124-3p
;
hsa-mir-132-3p
;
hsa-mir-221-3p
;
hsa-mir-376a-2-5p
;
hsa-mir-559
;
hsa-mir-548b-5p
;
hsa-mir-548a-5p
;
hsa-mir-548c-5p
;
hsa-mir-548d-5p
;
hsa-mir-548j-5p
;
hsa-mir-548h-5p
;
hsa-mir-548i
;
hsa-mir-548w
;
hsa-mir-3668
;
hsa-mir-3935
;
hsa-mir-548y
;
hsa-mir-548o-5p
;
hsa-mir-548ab
;
hsa-mir-548ad-5p
;
hsa-mir-548ae-5p
;
hsa-mir-548ak
;
hsa-mir-548am-5p
;
hsa-mir-5002-5p
;
hsa-mir-548ap-5p
;
hsa-mir-548aq-5p
;
hsa-mir-548ar-5p
;
hsa-mir-548as-5p
;
hsa-mir-548au-5p
;
hsa-mir-548ay-5p
;
hsa-mir-548bb-5p
;
hsa-mir-659-3p
;
hsa-mir-487b-5p
;
hsa-mir-487a-5p
;
hsa-mir-8054
;
hsa-mir-548l
;
hsa-mir-548k
;
hsa-mir-548av-5p
;
hsa-mir-497-3p
Nearest miRNA
hsa-mir-10525/Upstream/323110; hsa-mir-10399/Downstream/2043646;
Nearest TSS
ENST00000635602/Upstream/42696;
ENST00000460471/Downstream/102393;
Nearest CpG islands
None/Target,
chr7-CpG: 39/Upstream/53790
,
chr7-CpG: 71/Downstream/1233751
Upstream sequence
AGCAAATTCATCTCTAAATCAAACCATTGCACACCCGTAGAAATAGATCTCCTTTTACAGAGGCTTTGTAGATTTTAGTTATGAAAAGGGCATATATAAC
Downstream sequence
TGCTAAACAGATGTTTACTTTTAGACTATTATTCCTCTTTATCACTAAAGAACTGAAAAACGGTAACAGGATGTTCTATATTAGTTTTTATAAATCAGAT
Target sequence
ACTGTCTTTTTTGGCATCTTTTTAAATATGTATGCATAACTAGCTTTATGTTCAATAGCGGTCATTAGAATGTCATTCTAGTTGATACAAGAAGTTACAGAAGCAGCAAATTCATCTCTAAATCAAACCATTGCACACCCGTAGAAATAGATCTCCTTTTACAGAGGCTTTGTAGATTTTAGTTATGAAAAGGGCATATATAAC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT3
Sample type
PBMC
Age
52
Gender
Male
CpG Island Information
×
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