Basic Information
VIS ID
TVIS30016548
Fusion event
HIV-MDFIC integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q31.1
Reference genome
End
114616416/114976565 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-10525/Upstream/323110; hsa-mir-10399/Downstream/2043646;
Upstream sequence
AGCAAATTCATCTCTAAATCAAACCATTGCACACCCGTAGAAATAGATCTCCTTTTACAGAGGCTTTGTAGATTTTAGTTATGAAAAGGGCATATATAAC
Downstream sequence
TGCTAAACAGATGTTTACTTTTAGACTATTATTCCTCTTTATCACTAAAGAACTGAAAAACGGTAACAGGATGTTCTATATTAGTTTTTATAAATCAGAT
Target sequence
ACTGTCTTTTTTGGCATCTTTTTAAATATGTATGCATAACTAGCTTTATGTTCAATAGCGGTCATTAGAATGTCATTCTAGTTGATACAAGAAGTTACAGAAGCAGCAAATTCATCTCTAAATCAAACCATTGCACACCCGTAGAAATAGATCTCCTTTTACAGAGGCTTTGTAGATTTTAGTTATGAAAAGGGCATATATAAC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate