Basic Information
VIS ID
TVIS30016550
Fusion event
HIV-ING3 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q31.31
Reference genome
GRCh37/hg19
Start
120602370/120962316 (Hg38)
End
120602311/120962316 (Hg38)
Orient
-
Location type
Intronic
Target gene
ING3
miRNAs that regulate target gene
hsa-mir-378a-5p
Nearest miRNA
hsa-mir-10525/Upstream/3941997; hsa-mir-10399/Downstream/6095772;
Nearest TSS
ENST00000635602/Upstream/11200; ENST00000497502/Downstream/5180;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/11042, chr7-CpG: 81/Downstream/367217
Nearest cancer related gene
ING3(TSG, No orient, 0)
Upstream sequence
CAGCAGTAGTAAATAGAAGAAAAATAATGCTCATTGCCTAATAATTGCTTATAATATTAATCAGGTCATAATCTCTTTTACATATGAGGAAGTAAGAATG
Downstream sequence
ATTGGAAGCCGTCTTATAAAGATGCCTACCACAAGTGGTTAAGGCTTTTCTGTCTTTGTTTATTTTAACTATGAATTTGGTTTTTAGAGTTATTAACCCT
Target sequence
TAATTGCTTATAATATTAATCAGGTCATAATCTCTTTTACATATGAGGAAGTAAGAATG
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate