Basic Information
VIS ID
TVIS30016551
Fusion event
HIV-ZNF800 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q31.33
Reference genome
GRCh37/hg19
Start
127011534/127371480 (Hg38)
End
127011444/127371480 (Hg38)
Orient
-
Location type
Exonic
Target gene
ZNF800
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-128-3p ; hsa-mir-101-3p ; hsa-mir-27a-3p ; hsa-mir-106b-5p ; hsa-mir-20a-5p ; hsa-mir-527 ; hsa-mir-518a-5p ; hsa-mir-4473 ; hsa-mir-513a-5p ; hsa-mir-4671-3p ; hsa-mir-27b-3p ; hsa-mir-216a-3p ; hsa-mir-3681-3p ; hsa-mir-144-3p ; hsa-mir-454-3p ; hsa-mir-130a-3p ; hsa-mir-130b-3p ; hsa-mir-301a-3p ; hsa-mir-301b-3p ; hsa-mir-3666 ; hsa-mir-4295 ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-330-3p ; hsa-mir-6835-3p ; hsa-mir-3591-5p ; hsa-mir-153-5p ; hsa-mir-4680-5p ; hsa-mir-519d-5p ; hsa-mir-3145-5p ; hsa-mir-3646 ; hsa-mir-3662 ; hsa-mir-98-3p ; hsa-let-7f-1-3p ; hsa-let-7b-3p ; hsa-let-7a-3p ; hsa-mir-4326 ; hsa-mir-1284 ; hsa-mir-8067 ; hsa-mir-4666a-3p ; hsa-mir-6508-5p ; hsa-mir-381-3p ; hsa-mir-300 ; hsa-mir-3680-5p ; hsa-mir-4803 ; hsa-mir-519d-3p ; hsa-mir-93-5p ; hsa-mir-20b-5p ; hsa-mir-17-5p
Nearest miRNA
hsa-mir-10525/Upstream/313296; hsa-mir-10399/Downstream/710381;
Nearest TSS
ENST00000635602/Upstream/21352; ENST00000448311/Downstream/2085;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/23301, chr7-CpG: 122/Downstream/20320
Upstream sequence
GATGAAAATGTTGCCAAATAAAGAGAAACAAAACTAAAATCACTAAGATATAAAGTCTTTGTCAATTAAAAATTGATATTTTCTTCAGGTTGTTGATCAC
Downstream sequence
TTAATCAACAAATTGTTTAGAAAACAAAATTTGTAACATTTTTGTAGAAACTGTCGACCAAATGCACAAGGTCAAGGGTGGATAGCTGATGGACTGTGAT
Target sequence
TTGCCAAATAAAGAGAAACAAAACTAAAATCACTAAGATATAAAGTCTTTGTCAATTAAAAATTGATATTTTCTTCAGGTTGTTGATCAC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate