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TVIS30016553
Basic Information
VIS ID
TVIS30016553
Fusion event
HIV-UBE2H integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q32.2
Reference genome
GRCh37/hg19
Start
129497483/129857643 (Hg38)
End
129497446/129857643 (Hg38)
Orient
-
Location type
Intronic
Target gene
UBE2H
miRNAs that regulate target gene
hsa-mir-451a
;
hsa-mir-155-5p
;
hsa-mir-30a-5p
;
hsa-mir-1915-5p
;
hsa-mir-501-3p
;
hsa-mir-92a-3p
;
hsa-let-7e-5p
;
hsa-mir-4643
;
hsa-mir-218-5p
;
hsa-mir-6885-3p
;
hsa-mir-302c-5p
;
hsa-mir-3977
;
hsa-mir-6844
;
hsa-mir-3143
;
hsa-mir-5590-3p
;
hsa-mir-142-5p
;
hsa-mir-4803
;
hsa-mir-10a-3p
;
hsa-mir-548l
;
hsa-mir-8054
;
hsa-mir-548k
;
hsa-mir-548av-5p
;
hsa-mir-559
;
hsa-mir-548y
;
hsa-mir-548w
;
hsa-mir-548o-5p
;
hsa-mir-548j-5p
;
hsa-mir-548i
;
hsa-mir-548h-5p
;
hsa-mir-548d-5p
;
hsa-mir-548c-5p
;
hsa-mir-548bb-5p
;
hsa-mir-548b-5p
;
hsa-mir-548ay-5p
;
hsa-mir-548au-5p
;
hsa-mir-548as-5p
;
hsa-mir-548ar-5p
;
hsa-mir-548aq-5p
;
hsa-mir-548ap-5p
;
hsa-mir-548am-5p
;
hsa-mir-548ak
;
hsa-mir-548ae-5p
;
hsa-mir-548ad-5p
;
hsa-mir-548ab
;
hsa-mir-548a-5p
;
hsa-mir-4668-5p
;
hsa-mir-922
;
hsa-mir-5584-5p
;
hsa-mir-335-5p
;
hsa-mir-6838-5p
;
hsa-mir-497-5p
;
hsa-mir-424-5p
;
hsa-mir-195-5p
;
hsa-mir-16-5p
;
hsa-mir-15b-5p
;
hsa-mir-15a-5p
;
hsa-mir-2278
;
hsa-mir-342-3p
;
hsa-mir-4639-3p
;
hsa-mir-216b-3p
;
hsa-mir-603
;
hsa-mir-8485
;
hsa-mir-7156-3p
;
hsa-mir-6873-3p
;
hsa-mir-3941
;
hsa-mir-8064
;
hsa-mir-17-3p
;
hsa-mir-1205
;
hsa-mir-1184
;
hsa-mir-3158-5p
;
hsa-mir-6728-3p
;
hsa-mir-6817-3p
;
hsa-mir-7110-3p
;
hsa-mir-4691-3p
;
hsa-mir-449b-3p
;
hsa-mir-4789-3p
;
hsa-mir-377-3p
;
hsa-mir-1305
;
hsa-mir-498
;
hsa-mir-4465
;
hsa-mir-26b-5p
;
hsa-mir-26a-5p
;
hsa-mir-1297
;
hsa-mir-627-3p
;
hsa-mir-5697
;
hsa-mir-338-5p
;
hsa-mir-362-3p
;
hsa-mir-329-3p
Nearest miRNA
hsa-mir-10525/Upstream/82629; hsa-mir-10399/Downstream/638468;
Nearest TSS
ENST00000635602/Upstream/17902;
ENST00000480018/Downstream/1326;
Nearest CpG islands
None/Target,
chr7-CpG: 39/Upstream/31339
,
chr7-CpG: 88/Downstream/94549
Upstream sequence
CTAGACACACAGTTCCTGACCTGAAACAGATGGAAAGAATGGCATGTTTTTAAAAATTAGAAAGTTAGTTGCATGTATCTGGCAACTAATTTTTACTTAT
Downstream sequence
CAAGAGAAATACTTCTAATAGATCTGTGAAAAAAAGAATCCCAATtggggaaaagtatgatgaggaacagaatagtaccaggtcttgaagtgtcacctta
Target sequence
GTTAGTTGCATGTATCTGGCAACTAATTTTTACTTAT
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT1
Sample type
PBMC
Age
47
Gender
Male
CpG Island Information
×
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