Basic Information
VIS ID
TVIS30016561
Fusion event
HIV-MKLN1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q32.3
Reference genome
End
130859636/131175019 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
Target gene
miRNAs that regulate target gene
hsa-mir-128-3p ; hsa-mir-124-3p ; hsa-mir-101-3p ; hsa-mir-27a-3p ; hsa-mir-320b ; hsa-mir-324-5p ; hsa-mir-100-5p ; hsa-mir-142-3p ; hsa-mir-16-1-3p ; hsa-mir-144-3p ; hsa-mir-376c-5p ; hsa-mir-376b-5p ; hsa-mir-513a-5p ; hsa-mir-651-3p ; hsa-mir-1252-5p ; hsa-mir-3165 ; hsa-mir-5002-5p ; hsa-mir-6880-5p ; hsa-mir-8071 ; hsa-mir-142-5p ; hsa-mir-5590-3p ; hsa-mir-4496 ; hsa-mir-511-3p ; hsa-mir-297 ; hsa-mir-3924 ; hsa-mir-155-5p ; hsa-mir-5191 ; hsa-mir-3681-3p ; hsa-mir-216a-3p ; hsa-mir-3154 ; hsa-mir-223-5p ; hsa-mir-567 ; hsa-mir-340-5p ; hsa-mir-8054 ; hsa-mir-548l ; hsa-mir-548k ; hsa-mir-548av-5p ; hsa-mir-559 ; hsa-mir-548y ; hsa-mir-548w ; hsa-mir-548o-5p ; hsa-mir-548j-5p ; hsa-mir-548i ; hsa-mir-548h-5p ; hsa-mir-548d-5p ; hsa-mir-548c-5p ; hsa-mir-548b-5p ; hsa-mir-548bb-5p ; hsa-mir-548ay-5p ; hsa-mir-548au-5p ; hsa-mir-548as-5p ; hsa-mir-548ar-5p ; hsa-mir-548aq-5p ; hsa-mir-548ap-5p ; hsa-mir-548am-5p ; hsa-mir-548ak ; hsa-mir-548ae-5p ; hsa-mir-548ad-5p ; hsa-mir-548ab ; hsa-mir-548a-5p ; hsa-mir-548c-3p ; hsa-mir-5698 ; hsa-mir-744-3p ; hsa-mir-6805-3p ; hsa-mir-5691 ; hsa-mir-4423-5p ; hsa-mir-6501-5p ; hsa-mir-4430 ; hsa-mir-3652 ; hsa-mir-122-5p ; hsa-mir-504-3p ; hsa-mir-3135b ; hsa-mir-3194-3p ; hsa-mir-6499-3p ; hsa-mir-367-5p ; hsa-mir-1267 ; hsa-mir-6733-3p ; hsa-mir-143-5p ; hsa-mir-106a-3p ; hsa-mir-8055 ; hsa-mir-374b-3p ; hsa-mir-539-3p ; hsa-mir-485-3p ; hsa-mir-889-3p ; hsa-mir-548au-3p ; hsa-mir-449b-5p ; hsa-mir-449a ; hsa-mir-34c-5p ; hsa-mir-34a-5p ; hsa-mir-3140-3p ; hsa-mir-4686 ; hsa-mir-575 ; hsa-mir-4676-5p ; hsa-mir-6858-3p ; hsa-mir-3529-3p ; hsa-mir-5583-3p ; hsa-mir-4517
Nearest miRNA
hsa-mir-10525/Upstream/297480; hsa-mir-10399/Downstream/1859841;
Upstream sequence
CCCCACTTGTCTCCCTCCCTGATAACTGGtagatgatagatagatagatagatagatagatagatagatagatagatagatagatagatagggtgggtat
Downstream sequence
atagataggcagatggatggatggatggatggatggatggatggatggatggatggatggggagacagagagatagggtgggtggatggatggatgggtg
Target sequence
AGTTTCCAGTACAATTCAGACAGGGCAAGTCTGTTCTCTCCTCCCCACTTGTCTCCCTCCCTGATAACTGGtagatgatagatagatagatagatagatagatagatagatagatagatagatagatagatagggtgggtat
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate