Basic Information
VIS ID
TVIS30016564
Fusion event
HIV-PARP12 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q34
Reference genome
GRCh37/hg19
Start
139756502/140056702 (Hg38)
End
139756524/140056702 (Hg38)
Orient
+
Location type
Intronic
Target gene
PARP12
miRNAs that regulate target gene
hsa-mir-98-5p
Nearest miRNA
hsa-mir-10399/Upstream/1012545; hsa-mir-11400/Downstream/2417825;
Nearest TSS
ENST00000635602/Upstream/1939; ENST00000495590/Downstream/289;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/105822, chr7-CpG: 150/Downstream/5479
Upstream sequence
AATTCACTCACCATCAATACCAATTCACATTTGTCTAGGATGGCATGCTTGATCAAGTCTATGATTTCAACTTATCCTCACCCCCGCACTCCCTGCCTTG
Downstream sequence
ATTTTACTAAAAGCAGCACCAGACTTGCCCAAAGTCACACATTCCATGTAATGGCTAGCTGGAATCCGGGAACCCCCAGCCCAGGACCTCCCGTGCTCCC
Target sequence
TTAGGAAAGCATCATCAACTCC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate