Basic Information
VIS ID
TVIS30016569
Fusion event
HIV-GIMAP8 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q36.1
Reference genome
GRCh37/hg19
Start
150163000/150465912 (Hg38)
End
150162975/150465912 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA7I
Target gene
GIMAP8
miRNAs that regulate target gene
hsa-mir-1226-3p
Nearest miRNA
hsa-mir-10399/Upstream/3087791; hsa-mir-153-2/Downstream/772509;
Nearest TSS
ENST00000635602/Upstream/15282; ENST00000313543/Downstream/48918;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/57470, chr7-CpG: 44/Downstream/254414
Upstream sequence
tcgtaccactttgcatttaggtaatatgtggaaacttgcaaggtactttctcatttgtcatctcatttgagttttataaaaatatccttgaagtaggtaa
Downstream sequence
taccgcttctatcttatggattaggacactgagactcagaatggttaagtggcctctacagatctcagctaatgcgtgcagagcagaaggtgaaccaggt
Target sequence
ataaaaatatccttgaagtaggtaa
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate