Basic Information
VIS ID
TVIS30016572
Fusion event
HIV-chr7 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q36.1
Reference genome
GRCh37/hg19
Start
150318109/150621021 (Hg38)
End
150318292/150621021 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA7I
Nearest miRNA
hsa-mir-10399/Upstream/3242900; hsa-mir-153-2/Downstream/617400;
Nearest TSS
ENST00000635602/Upstream/53585; ENST00000487388/Downstream/11325;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/212579, chr7-CpG: 44/Downstream/99305
Nearby gene
GIMAP6(No orient, 4354)
Upstream sequence
acaacaaaattttcaagtttatttgagtaacaagcaattcatgaattggtaaacacacaaaccaaaagaggttcagcacgctgatgacaaagcatcagag
Downstream sequence
tcaagttaaattagtttaccagaaataacccaagttaagttttgcttatgttttgaatttaagcaacattaaagctatttttaatgcctagttggttggt
Target sequence
gcaagtatctataggatgaatgcagaagcagaatttaaaaattatttgattggttgctgttatgaatttaccttttctctttaccttgctggaaagttcatagtcacataatcatatgttgattggctgcttatgaatgactgagattaggttttgtttctgtctaagaaagacagaaatgac
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
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