Basic Information
VIS ID
TVIS30016586
Fusion event
HIV-PPP3CC integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
p21.3
Reference genome
GRCh37/hg19
Start
22363313/22505800 (Hg38)
End
22363340/22505800 (Hg38)
Orient
+
Location type
Intronic
Target gene
PPP3CC
miRNAs that regulate target gene
hsa-mir-6086 ; hsa-mir-6851-3p ; hsa-mir-377-5p ; hsa-mir-655-5p ; hsa-mir-6832-3p ; hsa-mir-3922-5p
Nearest miRNA
hsa-mir-124-1/Upstream/260763; hsa-mir-10400/Downstream/2447996;
Nearest TSS
ENST00000518652/Upstream/7801; ENST00000523620/Downstream/5108;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/64171, chr8-CpG: 107/Downstream/45359
Nearest cancer related gene
PPP3CC(TSG, No orient, 0)
Upstream sequence
ccgctataaggaaatgaagatccagagactcagagttgaacacttacatgctgaatcggacaaaaagtagtaagttgtgaaaaagtaactaaatgatgtg
Downstream sequence
aattcagtctcaactattaatccttggtgataacaatgttattttccttctagtacagggagggcatcttTTCTTTTttttttttaacttttattttagg
Target sequence
aggaggctagaagataagagttatttg
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate