Basic Information
VIS ID
TVIS30016587
Fusion event
HIV-chr8 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
p21.3
Reference genome
GRCh37/hg19
Start
23264245/23406732 (Hg38)
End
23264056/23406732 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-124-1/Upstream/1161695; hsa-mir-10400/Downstream/1547064;
Nearest TSS
ENST00000518652/Upstream/2492; ENST00000521021/Downstream/18559;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/2378, chr8-CpG: 81/Downstream/50456
Nearby gene
LOXL2(No orient, 2523)
Upstream sequence
cctctgattttttttactatatcattttgtgttaatttttcaatgtaatttttaatggttttagacagttctggtctgaaattattgtgcaatggagtca
Downstream sequence
tttctccattattggatattcagttgtttacagctttttgctagtgtaaattacgccatgacaattacccctgtGAAAGTAATATTTATTGATTGGGTAC
Target sequence
gggctgtccttgaactcctggtttcaagtgatccacccacctctgcctcccaaagtgctgggattacagacgtgagccacttcacctggcctctgattttttttactatatcattttgtgttaatttttcaatgtaatttttaatggttttagacagttctggtctgaaattattgtgcaatggagtca
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
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