Basic Information
VIS ID
TVIS30016595
Fusion event
HIV-chr8 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q12.2
Reference genome
GRCh37/hg19
Start
61831254/60918695 (Hg38)
End
61831108/60918695 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-124-1/Upstream/18022420; hsa-mir-10400/Downstream/796093;
Nearest TSS
ENST00000518652/Upstream/8105; ENST00000527672/Downstream/286;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/8226, chr8-CpG: 83/Downstream/3445
Nearby gene
LOC100130298(No orient, 47425)
Upstream sequence
ACTTGTCAAGTCACTTTTTTTGAGTGATTCCTATGCATAAACATTAACCAATATTTATGGAATGATCATATATTTTATTCCATTAGCAAGTAATTATAAC
Downstream sequence
CACTCAATAACATCTTGGAAAACTGAGATGAGAAAAAATCATTTACTCATAATCCTGCCATCCAAATAAAAACATAAACCATTTGATTTATTTCTTTTTA
Target sequence
TCTTATGCTTGTTCAAGTCACTGTTTTTTCAGAAAACAGAAATTGTACTTGTCAAGTCACTTTTTTTGAGTGATTCCTATGCATAAACATTAACCAATATTTATGGAATGATCATATATTTTATTCCATTAGCAAGTAATTATAAC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate