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TVIS30016599
Basic Information
VIS ID
TVIS30016599
Fusion event
HIV-ARFGEF1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
68139972/67227737 (Hg38)
End
68139810/67227737 (Hg38)
Orient
-
Location type
Intronic
Target gene
ARFGEF1
miRNAs that regulate target gene
hsa-mir-215-5p
;
hsa-mir-192-5p
;
hsa-mir-877-3p
;
hsa-mir-125a-3p
;
hsa-mir-10b-5p
;
hsa-mir-10a-5p
;
hsa-mir-19a-3p
;
hsa-mir-19b-3p
;
hsa-mir-3692-3p
;
hsa-mir-6727-3p
;
hsa-mir-4722-3p
;
hsa-mir-1228-3p
;
hsa-mir-424-3p
;
hsa-mir-27b-5p
;
hsa-mir-1254
;
hsa-mir-3116
;
hsa-mir-3690
;
hsa-mir-4638-3p
;
hsa-mir-4793-3p
;
hsa-mir-4797-5p
;
hsa-mir-508-5p
;
hsa-mir-5586-3p
;
hsa-mir-6512-3p
;
hsa-mir-6720-5p
;
hsa-mir-6849-3p
;
hsa-mir-759
;
hsa-mir-7703
Nearest miRNA
hsa-mir-124-1/Upstream/2848480; hsa-mir-10400/Downstream/7320806;
Nearest TSS
ENST00000518652/Upstream/16208;
ENST00000607397/Downstream/11017;
Nearest CpG islands
None/Target,
chr8-CpG: 109/Upstream/162524
,
chr8-CpG: 91/Downstream/115157
Upstream sequence
AGCAGTAAAAATCTACAATTCTTTATTTTTTGTTTTAGAAAAAGTATAGAATAGCATAGATAGGTAAATCCTAAGATTTTCCATAAAGGCATTAAGTATG
Downstream sequence
CTAAAACTATTTCTCAACAAGAAAAACAGATATTTTAAATCAAATTCTTAAAGCCCAGAGCAATCATTTCTAAAAAGAAAAACACCATTCACAGGGTTTT
Target sequence
TCTTCATTAGGATTACACCCAACCTGTAATGGCGACAGAAATAAACGATGCTAATTAATATCAGCAGTAAAAATCTACAATTCTTTATTTTTTGTTTTAGAAAAAGTATAGAATAGCATAGATAGGTAAATCCTAAGATTTTCCATAAAGGCATTAAGTATG
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT1
Sample type
PBMC
Age
47
Gender
Male
CpG Island Information
×
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