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TVIS30016603
Basic Information
VIS ID
TVIS30016603
Fusion event
HIV-DPY19L4 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
95754151/94741923 (Hg38)
End
95753827/94741923 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA8B
Target gene
DPY19L4
miRNAs that regulate target gene
hsa-mir-100-5p
;
hsa-mir-20a-5p
;
hsa-mir-142-3p
;
hsa-mir-576-5p
;
hsa-mir-744-3p
;
hsa-mir-4423-5p
;
hsa-mir-6501-5p
;
hsa-mir-3944-5p
;
hsa-mir-4430
;
hsa-mir-3652
;
hsa-mir-122-5p
;
hsa-mir-504-3p
;
hsa-mir-3135b
;
hsa-mir-367-5p
;
hsa-mir-1267
;
hsa-mir-4304
;
hsa-mir-596
;
hsa-mir-7151-3p
;
hsa-mir-5095
;
hsa-mir-365b-5p
;
hsa-mir-365a-5p
;
hsa-mir-8052
;
hsa-mir-3199
;
hsa-mir-6789-3p
;
hsa-mir-4707-3p
;
hsa-mir-6752-3p
;
hsa-mir-4258
;
hsa-mir-3620-3p
;
hsa-mir-4438
;
hsa-mir-4482-3p
;
hsa-mir-3679-3p
;
hsa-mir-6826-3p
;
hsa-mir-609
;
hsa-mir-138-2-3p
;
hsa-mir-1283
;
hsa-mir-4531
;
hsa-mir-5703
;
hsa-mir-4516
;
hsa-mir-4434
;
hsa-mir-539-5p
;
hsa-mir-1236-3p
;
hsa-mir-6515-3p
;
hsa-mir-5680
Nearest miRNA
hsa-mir-12123/Upstream/825804; hsa-mir-10400/Downstream/330988;
Nearest TSS
ENST00000518652/Upstream/2273;
ENST00000522669/Downstream/35755;
Nearest CpG islands
None/Target,
chr8-CpG: 109/Upstream/21863
,
chr8-CpG: 62/Downstream/81098
Upstream sequence
cttttgctgcagaagatttgtaaatagccatttctcattggcgctttggttccttttagtatagaatggaattagaaaatccagtctggcaactaggAGG
Downstream sequence
ACAAGATGATTTTTTGTTATGTCAGAAAGTGCCTGTTACAGGACATTTTGAGTTGCTGTGTACTTTTCTAAAATTCTATTAGGATTTATTTTTAGAAAGA
Target sequence
taagcatctttctgtacttatggatttttattgattcagtgattcattttaattgatttcattgattcagaacattttgatcaatgttcttctgttgctcaaattgtcacacccttggttaataggagtacctttcaggccggctcctgagttcttttgacacaactttgttaatctttgaaagctttcttgttttctggctcaacaaggtgagtaggtttgcacttttgctgcagaagatttgtaaatagccat
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT4
Sample type
PBMC
Age
39
Gender
Male
CpG Island Information
×
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