Basic Information
VIS ID
TVIS30016609
Fusion event
HIV-chr8 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q23.3
Reference genome
GRCh37/hg19
Start
116270149/115257920 (Hg38)
End
116269991/115257920 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-12123/Upstream/2614337; hsa-mir-10400/Downstream/1616808;
Nearest TSS
ENST00000518652/Upstream/975784; ENST00000415088/Downstream/234301;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/1825064, chr8-CpG: 33/Downstream/390285
Nearby gene
TRPS1(No orient, 150574)
Upstream sequence
AAAATAAATGAATTAAAAAAGAGTTGATTGATCGAAATTCATATCATGAATAAAATCTCGAAATGTTATGGCAATCAAAATAAACTTCAGTATTTGGATG
Downstream sequence
CAAAAAAAAAAAagagagagagagagagagagaACTAGCTCCTTTTAGCTGCTAGGTAGTTTTCCGTGTCAGCATATGGGAATGTTGTCTATATCCAAGA
Target sequence
CTTACAGAAAATATGACACACACAGGAAATTATACTTTAAGATTATGAGGATTCACAAAAAATAAATGAATTAAAAAAGAGTTGATTGATCGAAATTCATATCATGAATAAAATCTCGAAATGTTATGGCAATCAAAATAAACTTCAGTATTTGGATG
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate