Basic Information
VIS ID
TVIS30016610
Fusion event
HIV-EIF3H integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q23.3
Reference genome
GRCh37/hg19
Start
117680357/116668118 (Hg38)
End
117680473/116668118 (Hg38)
Orient
+
Location type
Intronic
Target gene
EIF3H
miRNAs that regulate target gene
hsa-mir-16-5p ; hsa-mir-511-5p ; hsa-mir-6830-3p ; hsa-mir-4423-3p ; hsa-mir-3613-3p ; hsa-mir-3622a-5p ; hsa-mir-5582-5p ; hsa-mir-5571-5p ; hsa-mir-6864-3p ; hsa-mir-3672 ; hsa-mir-6888-3p ; hsa-mir-196a-3p ; hsa-mir-661 ; hsa-mir-873-3p ; hsa-mir-4522 ; hsa-mir-302d-5p ; hsa-mir-302b-5p ; hsa-mir-3120-5p ; hsa-mir-6860 ; hsa-mir-612 ; hsa-mir-5189-5p ; hsa-mir-3187-5p ; hsa-mir-1285-3p ; hsa-mir-939-3p ; hsa-mir-6849-3p ; hsa-mir-3065-5p ; hsa-mir-520h ; hsa-mir-520g-3p ; hsa-mir-3664-5p ; hsa-mir-548ah-5p ; hsa-mir-3609
Nearest miRNA
hsa-mir-12123/Upstream/4024535; hsa-mir-10400/Downstream/206610;
Nearest TSS
ENST00000518652/Upstream/10343; ENST00000519443/Downstream/87666;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/998722, chr8-CpG: 21/Downstream/87573
Upstream sequence
TATTAACCCCATCCTCAAACTCTACTACTTCCATATTTTCTCCCTCAGTTAAGAGGATTTGAGCCGTCAATTGTGACTACTTCTCCAACACTCGGGTTAT
Downstream sequence
gcagaatataaaactataaaacatctataaatgccagtatgtaaacagtgtggactgcactctcctcctaaggagaaagactggaaagaaatatgctaaa
Target sequence
AATAGTCAACTACCTTCTGAGTAGACTTTGTTTTCCTCAAGGCAAAAATCATTTAGAACAtttctaaaaattttaaatggcataggaaaatgctcatgaggtgctaagagaaaaaa
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate