Basic Information
VIS ID
TVIS30016615
Fusion event
HIV-chr8 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q24.21
Reference genome
GRCh37/hg19
Start
129655369/128643123 (Hg38)
End
129655461/128643123 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-1204/Upstream/492935; hsa-mir-10400/Downstream/840934;
Nearest TSS
ENST00000518652/Upstream/546604; ENST00000519048/Downstream/322878;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/793145, chr8-CpG: 122/Downstream/1296003
Nearby gene
MIR1208(No orient, 492935)
Upstream sequence
aacaaaggctaacaagggaatctgaacatctactttcatctggcaataatgattcaggatcttttcttcccatcaacaccatttagggttttagccttgt
Downstream sequence
ttcttgggcagtagtaaaagttctgactctctactgggattcctctggcataaatccaggaaggagtgtagtggtgctgcattattgtcaggtgggaatg
Target sequence
tactgttggacagtagtaaaagttctaaagaagatgtgttcaacatcaacccgtcttctaccatcaacaccacaagggttttagctttgtta
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
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