Basic Information
VIS ID
TVIS30016622
Fusion event
HIV-MROH1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q24.3
Reference genome
GRCh37/hg19
Start
145282221/144227318 (Hg38)
End
145282263/144227318 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA8D
Target gene
MROH1
Nearest miRNA
hsa-mir-1204/Upstream/147376; hsa-mir-10400/Downstream/35355;
Nearest TSS
ENST00000518652/Upstream/28199; ENST00000528664/Downstream/11794;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/23944, chr8-CpG: 19/Downstream/11329
Upstream sequence
ttttttgttttcttgacttactacattggtgaagtctctagcatgctgctgaatgaatagaagtggtgagagcagccacccctgctttgttcccataagg
Downstream sequence
cgcagtggctcatgcctgtaatcccagcactttgggaggctgaggcgggcagatcattcaatctccttgagttcaggagttcaaaaccagcctggacaat
Target sequence
ggaacatactgccttttactattaagaatGCTGGGggctggg
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate