Basic Information
VIS ID
TVIS30016623
Fusion event
HIV-chr8 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q24.3
Reference genome
GRCh37/hg19
Start
145552800/144329137 (Hg38)
End
145552772/144329137 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA8D
Nearest miRNA
hsa-mir-1204/Upstream/11822; hsa-mir-10400/Downstream/65012;
Nearest TSS
ENST00000518652/Upstream/2227; ENST00000644270/Downstream/7144;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/1583, chr8-CpG: 584/Downstream/2542
Nearby gene
SCRT1(No orient, 1653)
Upstream sequence
GGCTTTGCCACCGGGGGTGGGGGCGTGGCGGGGCAGCAGCTCCAGAGGTGGGTGAAGCCCTGCCCAGACAGGCCCTATACCCTGGGATCTAGGGTGAGGG
Downstream sequence
GAATGGTCAGGGTAGGTGAGGTTGGTTGGGGACAAGGGTGTGTATGGCTGGGTCATCGAGGAAAGCATGATGCAGATCACCCTGCTGGGGGCAGCAACAA
Target sequence
CCCTATACCCTGGGATCTAGGGTGAGGG
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate