Basic Information
VIS ID
TVIS30016624
Fusion event
HIV-ADCK5 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q24.3
Reference genome
GRCh37/hg19
Start
145613294/144388094 (Hg38)
End
145613316/144388094 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA8D
Target gene
ADCK5
Nearest miRNA
hsa-mir-1204/Upstream/70779; hsa-mir-10400/Downstream/6055;
Nearest TSS
ENST00000518652/Upstream/14018; ENST00000607491/Downstream/6143;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/13195, chr8-CpG: 129/Downstream/3966
Upstream sequence
gtgctgggattataggtgtgagccaccacacccggccTCCAACATTTTGTGAAAAACTTCAAACATACAGCAATGTTGAAAATGCTCTGTGAGGCAATGT
Downstream sequence
tgggaggccgaggagggcggatcacgaggtcaggagttcgagaccagcctgaccaacgtggagaaaccccatctctactaaagatagaaaaattagctgg
Target sequence
GAAATGCAATGTGAAAATGctt
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate