Basic Information
VIS ID
TVIS30016625
Fusion event
HIV-PPP1R16A integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q24.3
Reference genome
GRCh37/hg19
Start
145706371/144480988 (Hg38)
End
145706292/144480988 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA8D
Target gene
PPP1R16A
miRNAs that regulate target gene
hsa-mir-1-3p
Nearest miRNA
hsa-mir-10400/Upstream/18449; hsa-mir-6850/Downstream/310943;
Nearest TSS
ENST00000518652/Upstream/2637; ENST00000533829/Downstream/9042;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/2469, chr8-CpG: 111/Downstream/19089
Nearby gene
FOXH1(No orient, 4653)
Upstream sequence
tgatgggtttttttttttgacggagtctcatgctgtgtcgcccaggctggagtgcagtggcacgatcttggctcactgcaagctccgcctcctgggttca
Downstream sequence
caccattctcctgcctcagcctcccaagtagctgggactacaggcgcccaccaccacgcccggctaattttttgtatttttttagtagagtcggggtttc
Target sequence
ggagtctcatgctgtgtcgcccaggctggagtgcagtggcacgatcttggctcactgcaagctccgcctcctgggttca
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate