Basic Information
VIS ID
TVIS30016630
Fusion event
HIV-ZNF16 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q24.3
Reference genome
GRCh37/hg19
Start
146170620/144945234 (Hg38)
End
146170501/144945234 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA8D
Target gene
ZNF16
Nearest miRNA
hsa-mir-10400/Upstream/153243;
Nearest TSS
ENST00000518652/Upstream/43066; ENST00000530223/Downstream/2801;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/42564, chr8-CpG: 54/Downstream/5215
Upstream sequence
caaatttatgtatttttttctgagacagagcctcactccagttgcccaggctagagtgcagtggcatgatcttagctcactgcaacccttgcctaccagg
Downstream sequence
ttcaagcaattcttgtgcttcagccttccaagtaggtggaattacaggtatgtgccaccacacctggctaatttttgtacttttagtagagacagggttt
Target sequence
taggtgcttttttttttttcaaatttatgtatttttttctgagacagagcctcactccagttgcccaggctagagtgcagtggcatgatcttagctcactgcaacccttgcctaccagg
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate