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TVIS30016632
Basic Information
VIS ID
TVIS30016632
Fusion event
HIV-C8orf33 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q24.3
Reference genome
GRCh37/hg19
Start
146287378/145061992 (Hg38)
End
146287442/145061992 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA8D
Target gene
C8orf33
miRNAs that regulate target gene
hsa-mir-132-3p
;
hsa-mir-124-3p
;
hsa-mir-26b-5p
;
hsa-mir-24-3p
;
hsa-mir-744-5p
;
hsa-mir-324-5p
;
hsa-mir-23b-3p
;
hsa-mir-222-3p
;
hsa-mir-1827
;
hsa-mir-4524a-3p
;
hsa-mir-1253
;
hsa-mir-6511a-5p
;
hsa-mir-1910-3p
;
hsa-mir-5197-3p
;
hsa-mir-3674
;
hsa-mir-384
;
hsa-mir-3685
;
hsa-mir-7975
;
hsa-mir-5571-3p
;
hsa-mir-4795-3p
;
hsa-mir-374b-5p
;
hsa-mir-374a-5p
;
hsa-mir-4732-5p
;
hsa-mir-6832-5p
;
hsa-mir-4445-5p
;
hsa-mir-6766-3p
;
hsa-mir-4782-3p
;
hsa-mir-219a-5p
;
hsa-mir-508-3p
;
hsa-mir-3605-5p
;
hsa-mir-3679-5p
;
hsa-mir-1185-5p
;
hsa-mir-126-5p
;
hsa-mir-5692c
;
hsa-mir-5692b
;
hsa-mir-369-3p
;
hsa-mir-154-5p
;
hsa-mir-3159
;
hsa-mir-5586-3p
;
hsa-mir-500a-3p
;
hsa-mir-6873-3p
;
hsa-mir-6804-3p
;
hsa-mir-4766-5p
;
hsa-mir-1236-3p
;
hsa-mir-6515-3p
;
hsa-mir-6817-3p
;
hsa-mir-7110-3p
;
hsa-mir-6769b-3p
;
hsa-mir-4723-3p
;
hsa-mir-3183
;
hsa-mir-502-3p
;
hsa-mir-501-3p
;
hsa-mir-6800-3p
;
hsa-mir-3925-5p
;
hsa-mir-2115-3p
;
hsa-mir-4311
Nearest miRNA
hsa-mir-10400/Upstream/270001;
Nearest TSS
ENST00000518652/Upstream/9524;
Nearest CpG islands
None/Target,
chr8-CpG: 109/Upstream/8982
, None/Downstream
Nearby gene
C8orf33
(No orient, 5962)
Upstream sequence
ggggaaaaggaacatatgcccagtaagtataattttgagttgccccaactggtggtatacttacggctgcactgactaccataaaggcagccagaattat
Downstream sequence
ACgacccagtagcaaaccgacactgccagtcggcaagggaccaaaaacacctgtgggaacagcaataggtggctctccaggcagcagagaaatatctctg
Target sequence
attacccgtcgtttctggaatttctttttcttttaATAAATTTTCCTACTTAACCCAGTAGCAA
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT5
Sample type
PBMC
Age
44
Gender
Male
CpG Island Information
×
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