Basic Information
VIS ID
TVIS30016639
Fusion event
HIV-KIAA2026 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
p24.1
Reference genome
GRCh37/hg19
Start
6001941/6001941 (Hg38)
End
6002012/6001941 (Hg38)
Orient
+
Location type
Intronic
Target gene
KIAA2026
miRNAs that regulate target gene
hsa-let-7a-5p ; hsa-mir-8485 ; hsa-mir-323a-3p
Nearest miRNA
hsa-mir-101-2/Upstream/1151566; hsa-let-7a-1/Downstream/5885;
Nearest TSS
ENST00000422679/Upstream/33860; ENST00000437881/Downstream/5846;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/168680, chr9-CpG: 135/Downstream/5023
Upstream sequence
atgctccttggaacatggtcattcatgagctgaaccaagatttatcacctaaaatctgaaagtgattatgttttcccaatttgtagggggaaaaaactaa
Downstream sequence
CAAAAAAATCatgatataattaaaaacatatttcaggatgttgtgaaaatagtaccatgacttctaagtgttctgacaatggaacacgtttgagaCTCAT
Target sequence
gacactacatagaatttcttcaattaagggttccctcccattatttgttttaaacctttTAGATGTCCTAG
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
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