Basic Information
VIS ID
TVIS30016641
Fusion event
HIV-APTX integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
p21.1
Reference genome
GRCh37/hg19
Start
33021631/33021633 (Hg38)
End
33021711/33021633 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA9C
Target gene
APTX
miRNAs that regulate target gene
hsa-mir-342-3p ; hsa-mir-7977 ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-5693 ; hsa-mir-6783-3p ; hsa-mir-4279 ; hsa-mir-1343-3p ; hsa-mir-377-3p ; hsa-mir-23b-5p ; hsa-mir-23a-5p ; hsa-mir-6829-3p ; hsa-mir-6791-3p ; hsa-mir-2276-3p ; hsa-mir-1976 ; hsa-mir-3653-5p ; hsa-mir-1281 ; hsa-mir-6742-3p ; hsa-mir-6852-5p ; hsa-mir-939-3p ; hsa-mir-6747-3p ; hsa-mir-6727-3p ; hsa-mir-4722-3p ; hsa-mir-660-3p ; hsa-mir-4485-5p ; hsa-mir-1228-3p ; hsa-mir-6722-5p ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-383-3p ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-1304-3p ; hsa-mir-1307-3p ; hsa-mir-4638-5p ; hsa-mir-6741-3p ; hsa-mir-6890-3p ; hsa-mir-891a-3p
Nearest miRNA
hsa-mir-101-2/Upstream/4132678; hsa-let-7a-1/Downstream/87059;
Nearest TSS
ENST00000422679/Upstream/19992; ENST00000465677/Downstream/3354;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/1485, chr9-CpG: 79/Downstream/3451
Nearby gene
DNAJA1(No orient, 3577)
Upstream sequence
AAGTGGTggccaggtgtggtggctcacgcctataataccagcactttgggacaccaaggcaggacaactgcttgagcccaggagttcaagaacagcctgg
Downstream sequence
TTAGTGTTAGACAAACTAGTTTGCCATTTGGAGAAAAATAAAGATCAGTTACTTACAAATAATCCTCAGTCCTTACACCAAAATAACTTTCAGATGGAAT
Target sequence
gcaacataggaagaccctatctctgcacatacaaaaaAAAGGTTGGGGGGCGGATTTCACATTAGTCAGGAAAAATAAGA
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate