Basic Information
VIS ID
TVIS30016642
Fusion event
HIV-UBE2R2 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
33838529/33838531 (Hg38)
End
33838679/33838531 (Hg38)
Orient
+
Location type
Intronic
Target gene
UBE2R2
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-7-5p ; hsa-mir-103a-3p ; hsa-mir-93-3p ; hsa-mir-92a-3p
Nearest miRNA
hsa-mir-101-2/Upstream/370596; hsa-let-7a-1/Downstream/1769563;
Nearest TSS
ENST00000422679/Upstream/19736; ENST00000448245/Downstream/90304;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/20229, chr9-CpG: 75/Downstream/210110
Upstream sequence
TCTTCACGTTGAGTTGTATTTTAAGTGTTTCATGGTAAACTTTCCTGAGATGTTTGCTAATGTTAATCTGCTTAATAGTTTTTTTTTAAATTGAGGTGTA
Downstream sequence
atgcaagaaccgtacatttagctctttacctccttcttgtcctttgccctattgatggtatattttcttataaacctctaaagcaacagtattattgttt
Target sequence
TGTACATACAATAAAATGTGTATATCTTggctgggcatggtggctcacgcctgtgatcccagaacttcgggaggctgagacaggtggattatgGattcttaatttactacagtttagtttatgttagttggttttattacttcccaggaa
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate