Basic Information
VIS ID
TVIS30016644
Fusion event
HIV-UBAP1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
34203615/34203617 (Hg38)
End
34203431/34203617 (Hg38)
Orient
-
Location type
Intronic
Target gene
UBAP1
miRNAs that regulate target gene
hsa-mir-141-3p
Nearest miRNA
hsa-mir-101-2/Upstream/735682; hsa-let-7a-1/Downstream/1404477;
Nearest TSS
ENST00000422679/Upstream/24572; ENST00000359544/Downstream/16822;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/24135, chr9-CpG: 54/Downstream/114667
Upstream sequence
tcctcgtagtgcataaaggcaagtggggaagacagacaataaacaaaTCCTGAATAAATTGATAAGCTACAAATATATATTTGTTTCCATTTTATGTGTT
Downstream sequence
GGAATAGATTAAATAAAATAGGAATAATCTGTTTCTTAAATATTTAATAGAACTTTAAAGACATCTGTTCTGACATTTATTTTAGCATACACATATTTCA
Target sequence
attcattcagcaggagttactgagcactactgtggccgggcactatgcttggtgtaatggtgaatgagacagaagtggtatttgtcctcgtagtgcataaaggcaagtggggaagacagacaataaacaaaTCCTGAATAAATTGATAAGCTACAAATATATATTTGTTTCCATTTTATGTGTT
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate