Basic Information
VIS ID
TVIS30016649
Fusion event
HIV-chr9 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
q21.13
Reference genome
GRCh37/hg19
Start
77998950/75384034 (Hg38)
End
77999153/75384034 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-101-2/Upstream/4573950; hsa-let-7a-1/Downstream/8585714;
Nearest TSS
ENST00000422679/Upstream/295491; ENST00000455583/Downstream/195635;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/295131, chr9-CpG: 148/Downstream/506280
Nearby gene
MIR548H3(No orient, 119561)
Upstream sequence
actgtagactcagctctttctctgccctgttaaataacccgagcatgtcatttggtctcttagccctGCCCCCTACATAACTGTTCACCTGCAGAATGTG
Downstream sequence
TCAGTGAACGGAAAAATATTCTAGAGGGTAGTGAGCTTCCCATGTGCTTAAGCACATATGGTGCAGGTGATAACGTACTCCATCTCTGTAAAGAAGGTTG
Target sequence
AAAACTTTATCAGCTCATCAATAAGGTTTTGTTAAGGAGCAAGCATCTATTGACCAAACTGGCTTATAACCCAAAAGATGCAGGGTCAGTTCTTGGCAAAACTATGAGGAAGGAAAAAAAATTGGCACTGTTTCCTGACTTCCGTATTTCTAAATCACCATTTTGAAGGCAAAAAGCTCAAAATTTGGTACTTCTGATATTAT
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate