Basic Information
VIS ID
TVIS30016653
Fusion event
HIV-chr9 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
q22.2
Reference genome
GRCh37/hg19
Start
92684321/89922039 (Hg38)
End
92684498/89922039 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-101-2/Upstream/609733; hsa-let-7a-1/Downstream/101402;
Nearest TSS
ENST00000422679/Upstream/118978; ENST00000446201/Downstream/56243;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/245430, chr9-CpG: 20/Downstream/720655
Upstream sequence
CTACCCTGAAGTTTTTGCTAGTCTTTGTGCATGACATTCAAAATAACGTACTTCTGCCACTACAAGGTGTGAGCACACTTCTAAATGACAAAATGATTGA
Downstream sequence
GAGAAAAGCGATTGTATCTGGATGTCCTCAGCCCTTTCCCCTCCAAATAGGCTGTGTGGTGAGTGCTCCTTCGAATGGTACAGATGGCCGGCCTGTTTAT
Target sequence
GTTATCATCAAGATATTGTTCAGTATAAACATCATTTTACTTTTCTAAACTTTTAAAAGTGGCCAACACATTCAGTCGCTGTATTATCTTTTGATTAACCCAAGTGCTCAGCTATCCATCGCATTCCACGAAGTCAGTTTGCAATTAATGAGCAGGACACAGTTTATCAGCATGCCT
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate