Basic Information
VIS ID
TVIS30016656
Fusion event
HIV-FAM120A integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
q22.31
Reference genome
GRCh37/hg19
Start
96219534/93457252 (Hg38)
End
96219411/93457252 (Hg38)
Orient
-
Location type
Intronic
Target gene
FAM120A
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-124-3p ; hsa-mir-93-3p ; hsa-mir-615-3p ; hsa-mir-18a-3p
Nearest miRNA
hsa-mir-101-2/Upstream/929194; hsa-let-7a-1/Downstream/137589;
Nearest TSS
ENST00000422679/Upstream/3660; ENST00000475933/Downstream/72218;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/4581, chr9-CpG: 21/Downstream/58818
Upstream sequence
ttgcttccactttttgactattgggaataatgaataatgcttctatgagcatagtatacaaagagctgttcgagttcctgctttcagttcttttgggtat
Downstream sequence
atactcagaagtaggattgctgggtcatatggtaattctgtttttctttttaaggaatggccatatattttccacagtggctgtGTAGGCCATATATTTT
Target sequence
tcatccactggtggatacttgggttgcttccactttttgactattgggaataatgaataatgcttctatgagcatagtatacaaagagctgttcgagttcctgctttcagttcttttgggtat
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate