Basic Information
VIS ID
TVIS30016658
Fusion event
HIV-ERCC6L2 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
q22.32
Reference genome
GRCh37/hg19
Start
98654262/95891980 (Hg38)
End
98654309/95891980 (Hg38)
Orient
+
Location type
Intronic
Target gene
ERCC6L2
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-3162-3p ; hsa-mir-6771-3p ; hsa-mir-6513-5p ; hsa-mir-887-5p ; hsa-mir-3913-5p ; hsa-mir-3122 ; hsa-mir-450a-1-3p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-7977 ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-7154-3p ; hsa-mir-5004-5p ; hsa-mir-383-3p ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-3714 ; hsa-mir-122-3p ; hsa-mir-1915-3p ; hsa-mir-1976 ; hsa-mir-2276-3p ; hsa-mir-3194-3p ; hsa-mir-3653-5p ; hsa-mir-4279 ; hsa-mir-4722-3p ; hsa-mir-4726-3p ; hsa-mir-5001-3p ; hsa-mir-6727-3p ; hsa-mir-6747-3p ; hsa-mir-6764-5p ; hsa-mir-6778-3p ; hsa-mir-6791-3p ; hsa-mir-6796-3p ; hsa-mir-6829-3p ; hsa-mir-6836-3p ; hsa-mir-6840-3p ; hsa-mir-6890-3p
Nearest miRNA
hsa-let-7a-1/Upstream/805886; hsa-mir-12126/Downstream/1471574;
Nearest TSS
ENST00000422679/Upstream/15837; ENST00000426805/Downstream/23821;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/15817, chr9-CpG: 122/Downstream/128954
Upstream sequence
ttttttaatttcattgtctttattgttgagttgtaagaatttttatgtattttggatactaatccctcatcagatatatgatttgcaaatattttctctc
Downstream sequence
gaaagttaagttttatgaagtccaatctgtttttttatttggttgaacaagttgtaattttaatgtATGTGTAAATAAATTTAAAAAATAGGACTATTAT
Target sequence
attctatagttgtctttttatttgcttgttattttactttgatgcac
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate