Basic Information
VIS ID
TVIS30016660
Fusion event
HIV-HABP4 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
q22.32
Reference genome
GRCh37/hg19
Start
99234071/96471789 (Hg38)
End
99234095/96471789 (Hg38)
Orient
+
Location type
Intronic
Target gene
HABP4
miRNAs that regulate target gene
hsa-mir-130b-3p ; hsa-mir-19b-3p ; hsa-mir-130a-3p ; hsa-mir-301a-3p ; hsa-mir-519c-3p ; hsa-mir-519b-3p ; hsa-mir-519a-3p ; hsa-mir-454-3p ; hsa-mir-301b-3p ; hsa-mir-4295 ; hsa-mir-3666 ; hsa-mir-323a-5p ; hsa-mir-578 ; hsa-mir-4775 ; hsa-mir-30e-5p ; hsa-mir-30d-5p ; hsa-mir-30c-5p ; hsa-mir-30b-5p ; hsa-mir-30a-5p ; hsa-mir-520e ; hsa-mir-520d-3p ; hsa-mir-520c-3p ; hsa-mir-520b ; hsa-mir-520a-3p ; hsa-mir-373-3p ; hsa-mir-372-3p ; hsa-mir-302e ; hsa-mir-302d-3p ; hsa-mir-302c-3p ; hsa-mir-302b-3p ; hsa-mir-302a-3p
Nearest miRNA
hsa-let-7a-1/Upstream/1385695; hsa-mir-12126/Downstream/891765;
Nearest TSS
ENST00000422679/Upstream/21584; ENST00000466976/Downstream/11236;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/20564, chr9-CpG: 61/Downstream/24723
Upstream sequence
AGTGTCTTGTCCCCTCTGTGCTCTCCCAGTCCTCCCTCCCTCTCTTTTCATTATGTAGCTTAGATACCGGCTCCGTCTCCAGCACCCTTCCAAGTTCTGT
Downstream sequence
gagtttcactcttattgcccaggctggagtgcaatggcgcgatcttggctcactgcaacctccacctcccagattcaagcaattctcctcctcagcctcc
Target sequence
TTTTCTGGGGttttttttgagaca
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate