Basic Information
VIS ID
TVIS30016662
Fusion event
HIV-MAPKAP1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
q33.3
Reference genome
GRCh37/hg19
Start
128427322/125665043 (Hg38)
End
128427197/125665043 (Hg38)
Orient
-
Location type
Intronic
Target gene
MAPKAP1
miRNAs that regulate target gene
hsa-mir-375 ; hsa-mir-26b-5p
Nearest miRNA
hsa-let-7a-1/Upstream/971245; hsa-mir-12126/Downstream/2025644;
Nearest TSS
ENST00000422679/Upstream/7333; ENST00000492314/Downstream/4802;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/256170, chr9-CpG: 58/Downstream/41783
Upstream sequence
tctgagcaccagttttctcacctgtaaaagagacatactaacagctaatttactggctttgaatgaagatgaaatAggccaggcacagtggctcacacct
Downstream sequence
gtaatcccaacactttgggaggccgaggcgggcggatcacatgaggccaggagttcaagatcagcctggccaacatgacaaaaccctgcctctactaaaa
Target sequence
agtaacttgggaaagttatttggcctctgagcaccagttttctcacctgtaaaagagacatactaacagctaatttactggctttgaatgaagatgaaatAggccaggcacagtggctcacacct
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate