Basic Information
VIS ID
TVIS30016666
Fusion event
HIV-NAIF1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
q34.11
Reference genome
GRCh37/hg19
Start
130827432/128065153 (Hg38)
End
130827327/128065153 (Hg38)
Orient
-
Location type
Intronic
Target gene
NAIF1
miRNAs that regulate target gene
hsa-mir-4433b-5p ; hsa-mir-7973 ; hsa-mir-4433a-5p ; hsa-mir-8064 ; hsa-mir-6846-3p ; hsa-mir-6859-3p ; hsa-mir-3182 ; hsa-mir-6810-3p ; hsa-mir-6801-3p ; hsa-mir-6884-3p ; hsa-mir-4717-3p ; hsa-mir-6834-3p ; hsa-mir-4640-3p ; hsa-mir-125a-5p
Nearest miRNA
hsa-let-7a-1/Upstream/195658; hsa-mir-12126/Downstream/179568;
Nearest TSS
ENST00000422679/Upstream/1411; ENST00000472769/Downstream/1131;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/83946, chr9-CpG: 103/Downstream/2103
Upstream sequence
GACTCTACACACGCTCTTTGCAGCCACATTAGTCCTACCTCCTTTGATGCtttctgcttttttttttttttttgagacggagttttgctcttttgccctg
Downstream sequence
ttacccaggttggagttcagtggcacgatctcggctcactgcaacttctgcctcccaggttcaagtgattgttgtgcctcagcctcccgagtagctggga
Target sequence
GGTGGGACTCTACACACGCTCTTTGCAGCCACATTAGTCCTACCTCCTTTGATGCtttctgcttttttttttttttttgagacggagttttgctcttttgccctg
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate