Basic Information
VIS ID
TVIS30016680
Fusion event
HIV-ABL1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
q34.12
Reference genome
End
133706051/130830796 (Hg38)
Orient
-
Location type
Intronic
Target gene
Nearest miRNA
hsa-let-7a-1/Upstream/204433; hsa-mir-126/Downstream/2114911;
Nearest cancer related gene
ABL1(OG, No orient, 0)
Upstream sequence
agctactgtttatcgagcaccttctgtgctttgggcactctccctacatgattcctaatcttcataataaccctgtgagataactactcttatgactacc
Downstream sequence
tcccatttttcagatgagaaaattgaggctctgagaggtgaagtcgttgcccatggccccacagtgagtggcagatctgagactcAGCGCTAGCCTTTGT
Target sequence
TACAGAAATAGTCCTCTTTTGGAaataacaatagctactgtttatcgagcaccttctgtgctttgggcactctccctacatgattcctaatcttcataataaccctgtgagataactactcttatgactacc
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate