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TVIS30016680
Basic Information
VIS ID
TVIS30016680
Fusion event
HIV-ABL1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
q34.12
Reference genome
GRCh37/hg19
Start
133706183/130830796 (Hg38)
End
133706051/130830796 (Hg38)
Orient
-
Location type
Intronic
Target gene
ABL1
miRNAs that regulate target gene
hsa-mir-203a-3p
;
hsa-mir-29a-3p
;
hsa-mir-30a-5p
;
hsa-mir-484
;
hsa-mir-342-3p
;
hsa-mir-149-5p
;
hsa-mir-125b-5p
;
hsa-let-7b-5p
;
hsa-mir-4723-5p
;
hsa-mir-583
;
hsa-mir-1537-5p
;
hsa-mir-7854-3p
;
hsa-mir-218-5p
;
hsa-mir-4999-5p
;
hsa-mir-4718
;
hsa-mir-4511
;
hsa-mir-548b-3p
;
hsa-mir-7111-5p
;
hsa-mir-6870-5p
;
hsa-mir-5698
;
hsa-mir-6825-5p
;
hsa-mir-7106-5p
;
hsa-mir-765
;
hsa-mir-423-5p
;
hsa-mir-5008-5p
;
hsa-mir-3184-5p
;
hsa-mir-4779
;
hsa-mir-4695-5p
;
hsa-mir-6891-5p
;
hsa-mir-3173-3p
;
hsa-mir-1233-5p
;
hsa-mir-17-3p
;
hsa-mir-185-3p
;
hsa-mir-1908-5p
;
hsa-mir-221-5p
;
hsa-mir-3621
;
hsa-mir-3622b-5p
;
hsa-mir-4300
;
hsa-mir-4418
;
hsa-mir-4492
;
hsa-mir-4498
;
hsa-mir-4508
;
hsa-mir-455-3p
;
hsa-mir-4720-5p
;
hsa-mir-4781-5p
;
hsa-mir-4799-3p
;
hsa-mir-5001-5p
;
hsa-mir-509-3-5p
;
hsa-mir-509-5p
;
hsa-mir-5588-5p
;
hsa-mir-5591-5p
;
hsa-mir-6090
;
hsa-mir-663a
;
hsa-mir-6726-5p
;
hsa-mir-6778-5p
;
hsa-mir-6787-5p
;
hsa-mir-6802-5p
;
hsa-mir-6815-5p
;
hsa-mir-6827-5p
;
hsa-mir-6865-5p
;
hsa-mir-744-5p
;
hsa-mir-762
;
hsa-mir-8073
;
hsa-mir-920
Nearest miRNA
hsa-let-7a-1/Upstream/204433; hsa-mir-126/Downstream/2114911;
Nearest TSS
ENST00000422679/Upstream/116816;
ENST00000318560/Downstream/4270;
Nearest CpG islands
None/Target,
chr9-CpG: 64/Upstream/117282
,
chr9-CpG: 106/Downstream/4077
Nearest cancer related gene
ABL1
(OG, No orient, 0)
Upstream sequence
agctactgtttatcgagcaccttctgtgctttgggcactctccctacatgattcctaatcttcataataaccctgtgagataactactcttatgactacc
Downstream sequence
tcccatttttcagatgagaaaattgaggctctgagaggtgaagtcgttgcccatggccccacagtgagtggcagatctgagactcAGCGCTAGCCTTTGT
Target sequence
TACAGAAATAGTCCTCTTTTGGAaataacaatagctactgtttatcgagcaccttctgtgctttgggcactctccctacatgattcctaatcttcataataaccctgtgagataactactcttatgactacc
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT1
Sample type
PBMC
Age
47
Gender
Male
CpG Island Information
×
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