Basic Information
VIS ID
TVIS30016685
Fusion event
HIV-MED27 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
q34.13
Reference genome
GRCh37/hg19
Start
134935914/132060527 (Hg38)
End
134936026/132060527 (Hg38)
Orient
+
Location type
Intronic
Target gene
MED27
Nearest miRNA
hsa-let-7a-1/Upstream/1434164; hsa-mir-126/Downstream/885180;
Nearest TSS
ENST00000422679/Upstream/244335; ENST00000372179/Downstream/19118;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/218320, chr9-CpG: 33/Downstream/19046
Upstream sequence
AAAGGCCTTTCTCATCAGTTGGACAAATGTGCAGAGAGACGGCAAAATTTACTACTCCCCCTCCCACCCGACTGTGACCACTGCACGGTCCCACATGATG
Downstream sequence
TCAAACAAAATGTTTCAAACATTTCCCAgctgggcgcagtggctcatgcctgtaatcccagcacactgggaggctgggacgggcagatcactgaaggtca
Target sequence
GCTCCATTTCTATAGAAGCTTCCTTCAAGGGCCGCCCTTTCCAAGCTTCTACAGGAAACCCTTTACGGTCCCCACCAAGCACACTGTGTTGCTCAACTGGAAAATTCAGTTT
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate